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Propagation of the PrP transition in cultured neural cells
Reference
BBS/E/I/00000653
Principal Investigator / Supervisor
Dr Christopher Birkett
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
38,630
Status
Completed
Type
Institute Project
Start date
01/09/1997
End date
31/08/2000
Duration
36 months
Abstract
The aims of the project are to investigate how the transition between the cellular and scrapie forms of the prion protein propagates between cultured neural cells and within neurones. This should lead to a detailed understanding of some of the interactions that mediate PrP- Sc deposition and hence affect pathogenesis. In the longer term this work may also provide test systems for agents which inhibit propagation.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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