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Antigenic epitopes on African swine fever virus
Reference
BBS/E/I/00000426
Principal Investigator / Supervisor
Dr Michael Parkhouse
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
33,470
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
30/09/1998
Duration
18 months
Abstract
Immunity to African swine fever virus has been shown to be due to both serological and cellular immune responses. In order to define the viral epitopes recognised by these protective immune responses, expression libraries of virus infected cells have been screened with (1) sera from recovered pigs to define serological epitopes and (2) CD8 T- cells in order to define cytotoxic T- cell epitopes. Both aims of the immune response have been demonstrated to recognise several different viral proteins and thus vaccine design will be complex, perhaps based on a disabled virus rather than a restricted number of recombinant viral proteins.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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