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Award details
Genetic vaccination of pigs
Reference
BBS/E/I/00000424
Principal Investigator / Supervisor
Dr Michael Parkhouse
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
170,306
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
30/09/2000
Duration
42 months
Abstract
Pathogens of farm animals provide realistic systems for the development of new generation vaccines for infectious diseases of natural hosts. Furthermore, the increasing awareness of the dangers of indiscriminate application of antibiotics in agriculture is an additional impetus towards the development of new vaccine approaches. In this work we have commenced an evaluation of genetic, or DNA, immunisation of pigs, using as a model system recombinant plasmids containing sequences coding for immunodominant epitopes of the economically important pathogen Foot-and- mouth disease virus (FMDV). To date, both serological and cellular immune responses have been observed in pigs vaccinated with such DNA vaccines. During the next year their efficacy as protective vaccines will be evaluated.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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