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Award details
Immunology and cell biology of African swine fever virus
Reference
BBS/E/I/00000405
Principal Investigator / Supervisor
Dr Michael Parkhouse
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
29,760
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
30/04/1997
Duration
1 months
Abstract
The objectives here are to prepare monoclonal antibodies to differentiation antigens of porcine macrophages and antigen- presenting cells, and establish MHC-defined porcine macrophage and endothelial cell lines; determine the range and location of cells infected in vivo; define key components involved in host virus-interaction: host and virus receptors for viral invasion and viral determinants expressed by infected host cells; characterise antigen processing and cytokine and surface antigen expression in cells infected with ASFV and define the immune response induced by the virus via comparative longitudinal studies of immune responses to the pathogenic versus non-pathogenic virus isolates.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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