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New molecular approaches for improved vaccines against poultry diseases
Reference
BBS/E/I/00000395
Principal Investigator / Supervisor
Professor Jim Kaufman
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
55,855
Status
Completed
Type
Institute Project
Start date
01/05/1997
End date
30/11/2000
Duration
43 months
Abstract
The peptide-binding specificity of the single dominantly- expressed class I molecule found in many common chicken MHC haplotypes can determine the immune response, and may therefore explain the importance of the B locus (the chicken MHC) in response to certain vaccines. In order to examine this issue, the experimental lines of chickens used in important research centres in the EU are being characterised with regard to 1. sequence, expression level and peptide- binding specificities of the MHC molecules, 2. the response to certain commercial vaccines to infectious bursal disease and Marek's disease, and 3. the dependence of these responses on the B locus.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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