BBSRC Portfolio Analyser
Award details
Quantitative analysis of Marek's disease vaccine virus in relation to host genetic resistance
Reference
BBS/E/I/00000379
Principal Investigator / Supervisor
Dr N Bumstead
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
35,099
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
30/09/1998
Duration
18 months
Abstract
This project seeks to investigate the replication of pathogenic and vaccine strains of Mareks disease virus (MDV) in birds of different genotypes, using a quantitative PCR approach. A modified assay using a Taqman probes has been developed to facilitate these comparisons. The time course of viral infection has been established for a range of vaccine and pathogenic strains. In each case large differences in replication have been observed in birds of different genotypes. There the extent of replication of pathogenic and attenuated strains of MDV correlates strongly across genotypes, indicating that measurement of the replication of vaccine virus can identify genetically resistant birds.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search