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Award details
Cell biology of normal and persistently infected T-cells
Reference
BBS/E/I/00000321
Principal Investigator / Supervisor
Professor Tom Wileman
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
459,688
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
31/03/2000
Duration
36 months
Abstract
The gamma delta T-cell specific orphan" receptor, WC1, is able to induce G1 growth arrest in proliferating IL-2 dependent gamma delta T-cells and as such may therefore play an important role in the regulation of gamma delta T-cell biology. This is being examined in detail and should provide further insight into the signalling mechanisms through which the activated orphan receptor, WC1, functions within the context of gamma delta T-cell biology by inducing G1 growth arrest in proliferating IL-2 dependent gamma delta T-cells.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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