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Influence of viral infection on the immune response
Reference
BBS/E/I/00000298
Principal Investigator / Supervisor
Professor Christopher Howard
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
64,995
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
30/09/1999
Duration
30 months
Abstract
Bovine virus diarrhoea virus, a member of the Flaviviridae, infection of cattle results in a variety of pathologies. An increased susceptibility to secondary infection has reported following infection with the virus and a transient immunosuppression. Bovine virus diarrhoea virus replicates in the hosts antigen presenting cells. This study is testing the hypothesis that infection of macrophages and dendritic cells alters the function of the cell and compromises their ability to stimulate T cells and will investigate the molecular basis for such an effect.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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