Award details

Generation and functional properties of dendritic cell lines

Reference	BBS/E/I/00000295
Principal Investigator / Supervisor	Professor Christopher Howard
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	26,739
Status	Completed
Type	Institute Project
Start date	01/04/1997
End date	31/12/1998
Duration	21 months

Abstract

The central role of dendritic cells makes them a target for strategies aimed at modulating the immune response for the benefit of the host and its protection from disease. The availability of lines of dendritic cells derived from MHC defined families of cattle would greatly facilitate investigations of antigen presenting cell function and the study of immunity to a variety of cattle diseases. This programme is determining the means by which dendritic cell lines can be generated from blood monocytes or bone marrow by culture with cytokines and whether the lines can be immortalised.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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