Award details

Avian B-cell development

Reference	BBS/E/I/00000284
Principal Investigator / Supervisor	Dr John Young
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	91,975
Status	Completed
Type	Institute Project
Start date	01/04/1997
End date	31/03/1998
Duration	12 months

Abstract

The development of antigen-responsive B-cells is crucial to the effectiveness of early vaccination. Development of B- cells in chickens is very different from the process in mammals. This project investigates the development and function of chicken B-cells, in order to contribute to genetic and other improvements in the effectiveness of early vaccination. A novel B-cell surface molecule, with no known mammalian homologue, has been identified and its gene structure determined. The expression and function in B- cells of the recently cloned chicken homologue of the costimulatory molecule CD80 are being studied. Collaborative work has shown that all chicken B-cells express CD5.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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