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Cell surface molecules on bovine dendritic cells and their function in interactions with T-lymphocytes
Reference
BBS/E/I/00000283
Principal Investigator / Supervisor
Professor Christopher Howard
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
13,147
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
30/09/1997
Duration
6 months
Abstract
Dendritic cells are the most effective antigen presenting cell and the only one recognised as being able to initiate immune responses in naive animals. Our previous studies have established that in tissues taken from cattle different sub- populations of dendritic cells can be identified by staining with monoclonal antibodies and that these sub- populations vary in their biological properties. This project is investigating the molecular basis for differences in dendritic cell biology aiming to clone, and define the properties of, potentially novel antigens, that are expressed by the dendritic cells or by sub- populations thereof.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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