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Identification of chicken CD28 ligands
Reference
BBS/E/I/00000282
Principal Investigator / Supervisor
Dr John Young
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
29,143
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
30/04/1997
Duration
1 months
Abstract
The co-stimulatory signal received by the CD28 receptor on T-cells is crucial in determining the outcome of recognition of foreign antigen by the antigen-specific T-cell receptor, which may be an effective response or the induction of anergy. Whilst CD28 has been identified in chickens and has been shown to deliver a co-stimulatory signal, nothing is known in this species about the ligands on antigen- presenting cells that engage CD28 on the T-cell to provoke the co- stimulatory signal. This project sets out to provide that information.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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