Award details

Molecular biology of animal influenza viruses

ReferenceBBS/E/I/00000256
Principal Investigator / Supervisor Dr John McCauley
Co-Investigators /
Co-Supervisors
Institution The Pirbright Institute
DepartmentThe Pirbright Institute Department
Funding typeResearch
Value (£) 415,162
StatusCompleted
TypeInstitute Project
Start date 01/04/1997
End date 31/03/2000
Duration36 months

Abstract

By using the defective viruses that we have accumulated in our earlier work our aim is to investigate whether an intracellular stage of a pathway that leads to virion assembly which may be inhibited in a segment-specific manner can be demonstrated. To use the drug 4- Guanidino-Neu5Ac2en to investigate the details of the interaction of the haemagglutinin and neuraminidase glycoproteins in tissue culture. To collaborate with Drs I Brown and D Alexander of the Veterinary Laboratories Agency on the genetic characterisation of these new swine influenza viruses which are likely to be of epidemiological significance.

Summary

unavailable
Committee Closed Committee - Animal Sciences (AS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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