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Interaction of rinderpest virus non-structural proteins with virus and host cell proteins

ReferenceBBS/E/I/00000251
Principal Investigator / Supervisor Dr Michael Baron
Co-Investigators /
Co-Supervisors
Institution The Pirbright Institute
DepartmentThe Pirbright Institute Department
Funding typeResearch
Value (£) 82,023
StatusCompleted
TypeInstitute Project
Start date 01/04/1997
End date 30/09/1999
Duration30 months

Abstract

Rinderpest virus, like all the morbilliviruses, produces two non- structural proteins (C&V) of unknown function. This project is aimed at elucidating the functions of these proteins by studying what other proteins they interact with. The yeast two-hybrid system is being used to investigate their binding with other cytoplasmic viral proteins; interactions that are discovered with this method will be confirmed by additional techniques. A cDNA library will be screened, where possible, to look for host cell proteins that may interact with C or V.

Summary

unavailable
Committee Closed Committee - Animal Sciences (AS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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