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Award details
Construction and characterisation of a resource population of pigs to map genes which influence resistance to salmonellosis
Reference
BBS/E/I/00000238
Principal Investigator / Supervisor
Dr Timothy Wallis
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
27,450
Status
Completed
Type
Institute Project
Start date
01/05/1998
End date
30/04/2000
Duration
24 months
Abstract
A resource family of pigs derived from pig lines resistant and susceptible to salmonellosis is being constructed and will be screened for susceptibility to salmonellosis following oral challenge with Salmonella choleraesuis. DNA samples from the individuals will be sampled for subsequent qualitative trait locus analysis. Individuals will be screened for polymorphisms in nramp1, LPS and sal1, genetic loci known to influence the susceptibility of other animal species to salmonellosis. Polymorphisms will be correlated to the bactericidal activity and cytokine responsiveness of macrophages, and susceptibility of macrophage donor animals to infection.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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