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Use of targeted RNA recombination for the mutagenesis of coronavirus genomes
Reference
BBS/E/I/00000181
Principal Investigator / Supervisor
Professor David Cavanagh
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
16,410
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
30/09/1998
Duration
18 months
Abstract
Infectious bronchitis virus (IBV) is a major pathogen of poultry and exists as many serotypes which do not induce sufficient cross-protection. The objective is to replace a gene of infectious bronchitis virus with the corresponding gene from another strain/serotype of IBV by means of targeted homologous recombination. The purpose is to study the role of IBV proteins in pathogenicity and the induction of protective immune responses.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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