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Analysis of transcription and replication signals in the rinderpest genome RNA
Reference
BBS/E/I/00000085
Principal Investigator / Supervisor
Professor Thomas Barrett
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
26,058
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
30/09/1997
Duration
6 months
Abstract
The sequences required for directing mRNA transcription and genome replication in rinderpest virus appear to be confined to short (50-100 base) sequences at each end of the viral genome. Minigenomes containing these sequences, and one or more reporter genes, are replicated and transcribed by helper virus, or using viral proteins expressed from plasmids. We are mutating individual residues and blocks of residues in the viral sequences and studying the effects on transcription of the reporter genes and replication of the minigenome.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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