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401d: Pathogenicity interactions at the plant/pathogen interface

Reference	BBS/E/H/00032645
Principal Investigator / Supervisor	Professor James Beynon
Co-Investigators / Co-Supervisors
Institution	University of Warwick
Department	Warwick HRI
Funding type	Research
Value (£)	619,700
Status	Completed
Type	Institute Project
Start date	01/04/2003
End date	31/03/2005
Duration	24 months

Abstract

The objectives of this project are to understand the fundamental bases of pathogenicity in oomycete plant pathogens, using the model system of the infection of Arabidopsis with the downy mildew pathogen Peronospora parasitica. This involves the identification of the genes/proteins (pathogenicity factors) that the pathogen uses to establish a successful infection and to usurp plant cellular function for its own benefit. These proteins have targets within the plant and the identification of these targets will reveal the plant processes that are disrupted or altered in favour of the pathogen. We wish to use this information to build a model showing how and where the pathogen proteins interact with the plant to repress defence or alter plant metabolism or transcription. Furthermore, classic disease resistance genes interact with these pathogenicity factors, either directly or via intermediary proteins, to initiate defence responses. Hence, we will use the RPP13 disease resistance genes to investigate how resistance responses are integrated with pathogenicity.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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