Award details

Development of molecular genetic technology and its application to food relevant micro-organisms

Reference	BBS/E/F/04331060
Principal Investigator / Supervisor	Dr D Archer
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	251,428
Status	Completed
Type	Institute Project
Start date	01/04/1999
End date	31/03/2000
Duration	12 months

Abstract

This project has the aim of developing molecular genetic technology for applications primarily with food-relevant micro organisms. The skill base within the project underpins molecular biology activities within each of the scientific themes at IFR and particularly with Food Quality and Food Safety Sciences. The micro organism focus is with food-use fungi and the Gram-positive lactic acid bacteria. Filamentous fungi are widely used commercially for supply of food- use enzymes and metabolites such as organic acids and long chain polyunsaturated fatty acids. Lactic acid bacteria are key organisms in the dairy products industries. Our aims are to identify the bottlenecks in production at the molecular level and to genetically modify these organisms in order to improve both the yield and variety of their products. Genes introduced into the genomes of bacteria and fungi exhibit locus-dependent expression. We aim to understand this effect and to devise strategies to ensure a predictable impact of introduced genes. Many fungi either used in food manufacture or which contaminate foods secrete potent toxins. One of our aims is to understand the regulation of toxin synthesis in order to ensure safe food products

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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