Award details

Safety Evaluation of GM Food

Reference	BBS/E/F/04331057
Principal Investigator / Supervisor	Dr Anthony Michael
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	370,534
Status	Completed
Type	Institute Project
Start date	01/07/1999
End date	30/06/2000
Duration	12 months

Abstract

This project is investigating the molecular consequences of the introduction of foreign genes into plants. A key concern with transgenic technology is whether the introduction and activity of a transgene will have unintended consequences that will influence the safety and nutritional characteristics of the GM material. We are examining key molecular parameters of transgenic plants: relative messenger RNA abundance as measured by high density cDNA arrays (in the model plant Arabidopsis); the relationship between mRNA and cognate protein encoded by that message is being examined using reporter genes and novel monsome/polysome differential screening of high density cDNA arrays; transgenic tomato plants have been created to examine the relationship between protein levels and metabolites using proteomic approaches. The key aspect of this project is that we are examining all processes from the abundance of message RNAs to the eventual production of proteins and metabolites using a multidisciplinary approach incorporating the new post-genomic technologies.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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