BBSRC Portfolio Analyser
Award details
Filamentous fungi as cell factory for the production of proteins and fungal metabolites
Reference
BBS/E/F/04330974
Principal Investigator / Supervisor
Dr D Archer
Co-Investigators /
Co-Supervisors
Institution
Quadram Institute Bioscience
Department
Quadram Institute Bioscience Department
Funding type
Research
Value (£)
107,492
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
30/11/1999
Duration
32 months
Abstract
This project is part of EUROFUNG, a large integrated project funded by the EU in the Biotechnology Programme. the IFR project is within the Protein Production part of EUROFUNG. Our aims are to understand at the molecular level the bottlenecks in achieving high secreted yields of target heterologous proteins. We have previously shown that filamentous fungi are excellent hosts for the production of heterologous proteins but that in some cases the yields of protein are low and that this is due to bottlenecks in the secretory pathway. The detailed knowledge we obtain will be used to produce recombinant fungal strains that are improved in their protein secretory pathway.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search