Award details

New methodologies for assessing the potential of unintended effects in genetically modified food crops (GMOCARE)

Reference	BBS/E/F/04211025
Principal Investigator / Supervisor	Dr Ian Colquhoun
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	175,557
Status	Completed
Type	Institute Project
Start date	01/02/2000
End date	31/07/2003
Duration	42 months

Abstract

Market introduction of genetically modified (GM) food crops in Europe has given rise to broad public concern, a great deal of which is based on uncertainties related to safety for humans, animals and environment. One of the key issues in the risk assessment of GM crop plants is whether unexpected hazardous metabolic perturbations (so-called unintended effects) may have taken place in the organism due to genetic modification that could affect its food or nutritional status. It is recognised that adequate and effective animal models to identify and trace the sources of potential unintended effects do not exist. The objective of the project is to develop new methodologies that are of sufficient sensitivity and specificity to assess risks from this possible food borne hazard. Implicit in this objective is the need to develop new knowledge intended to understand the implications of the genetic modification process on metabolic pathways in plants. Strong emphasis is placed on the exploitation of combinative and innovative 'cell factory' technologies (genomics, proteomics and metabolomics). IFR¿s role in the project is to apply new methods of metabolite profiling based on a combination of analytical techniques (NMR, HPLC) and chemometrics

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search