Award details

Immunochemistry

Reference	BBS/E/F/04131041
Principal Investigator / Supervisor	Dr Gary Wyatt
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	188,210
Status	Completed
Type	Institute Project
Start date	01/05/1999
End date	31/03/2000
Duration	11 months

Abstract

The unique nature of antibody interactions with their targets are being explored with in vivo and in vitro applications. The nature of the IgE and IgG responses to food allergens are being used to define the role of individual allergens in allergy, and to gain further insight into the sensitisation process. Research on the interaction of peptides and peptide epitopes with antibodies will generate opportunities for generation of novel antibodies. A further application of the work is the development of immunological methods of analysis for compounds which are difficult to analyse by alternative procedures and which can be used to study processing- induced changes in structure. Strategies for rational changes in the recognition properties of recombinant antibodies are being pursued, underpinned by modelling of antibody structure.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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