Award details

Rapid immunochemical test methods for a screening system to monitor pesticide and antibiotic residues in food and food products

Reference	BBS/E/F/04130933
Principal Investigator / Supervisor	Dr Gary Wyatt
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	108,143
Status	Completed
Type	Institute Project
Start date	01/04/1997
End date	31/08/2000
Duration	41 months

Abstract

The main goal of the present project is the development of screening systems in which two complementary methods, sol particle immunoassays (SPIAs) and biosensors, will be applied to monitor pesticide and antibiotic residues both in raw and processed food and in food products. The specific combination of test methods proposed ensures that it will be possible to monitor residues throughout the production chain, irrespective of the skills of the person performing the test and also irrespective of the level of laboratory equipment available. An important and fundamental part of the project will be devoted to the development of generic, group oriented monoclonal and recombinant antibodies, recognising a whole group of particular pesticide or antibiotic residues with a common structural moiety. This can be done by combining various poly- or monoclonal antibodies each specific for a particular member of a residue group, or by using a generic chemical structural motif, common to all members in a residue group, for immunisation procedures. Recombinant antibody fragments will also be used, offering the possibility of mutating these antibody-fragments. In this way, the affinity and/or specificity of the antibody can be altered, giving rise to more broadly specific recombinant antibodies, as required

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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