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Effects of foodborne glucosinolates on human health
Reference
BBS/E/F/04117094
Principal Investigator / Supervisor
Dr Ian Johnson
Co-Investigators /
Co-Supervisors
Professor Gary Williamson
Institution
Quadram Institute Bioscience
Department
Quadram Institute Bioscience Department
Funding type
Research
Value (£)
146,702
Status
Completed
Type
Institute Project
Start date
01/10/1997
End date
30/09/2000
Duration
36 months
Abstract
The general objective of this EU Shared-Cost project (PL 96 3029) is to determine whether the protective effects of glucosinolates and their breakdown products (principally isothiocyanates) from Brassica vegetables are of practical value in the maintenance of human health in Europe. A further aim is to assess whether glucosinolates are an appropriate target for enhancement by genetic manipulation of commercial vegetable varieties. Thus the project is aimed at consumers who will benefit from an increased understanding of the relationship between an important class of vegetables and health, and at food producers who will ultimately be able to assess the feasibility and cost effectiveness of new varieties of brassica vegetables with enhanced nutritional value. In collaboration with other European partners we will assess the quantities of isothiocyanates reaching various regions of the alimentary tract, their availability for interaction with the intestinal mucosa, and their metabolic activity, particularly with regard to the induction of Phase II enzymes in the liver
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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