Award details

Speciation and bioavailability of selenium from processed and tailor made fishery products

Reference	BBS/E/F/04108770
Principal Investigator / Supervisor	Professor Susan Jane Fairweather-Tait
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	3,499
Status	Completed
Type	Institute Project
Start date	01/04/1997
End date	31/10/1999
Duration	31 months

Abstract

The overall aim of this project is to improve the knowledge and understanding of the chemical forms of selenium found in fish and fish products and to analyze their effect on the absorption and metabolism of selenium in humans. Specific objectives will include, 1) studying the effect of fish farming methods and food processing methods in fishery products on the chemical character of selenium in fish. 2) relating the chemical characterization of selenium found in the different fish products to human nutrition. 3) investigating the metabolism of selenium from fish products in humans to optimize the nutritional selenium status of the consumer. IFR will be contributing to this study in two areas, namely the intrinsic labelling of fish with stable isotopes of selenium and the development of double isotope labelling techniques to study the absorption and metabolism of selenium from the diet in humans. We will be using our experience of labelling cod fish with a stable isotope of selenium to assist in the protocol design to intrinsically label fresh water and sea water fish with stable isotopes of selenium for use in the metabolic studies in humans. The human metabolic studies will involve feeding intrinsically labelled fish to volunteers and estimating absorption of selenium by measuring the selenium stable isotope both in the food and in the faeces. Other human studies will involve feeding labelled fish to volunteers together with a labelled source of inorganic selenium and analyzing the chemical character of the two different sources of selenium in the urine, plasma and faecal samples

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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