Award details

Modelling and characterisation of primary flavour perception

Reference	BBS/E/F/03350858
Principal Investigator / Supervisor	Professor Ian Connerton
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	226,515
Status	Completed
Type	Institute Project
Start date	01/04/1997
End date	30/09/1998
Duration	18 months

Abstract

The human genome is thought to contain as many as 500 different genes for flavour receptors, yet only a few have been identified and none characterised. This project involves the cloning and functional expression of genes involved in the primary reception of odorant and taste molecules, including the specific identification of a sweet taste receptor. All known vertebrate olfactory receptors and many gustatory receptors share a common seven transmembrane structure. A model system to study such receptors in yeast is being developed as part of an existing project at IFR. This system will be used to identify specific ligands for flavour receptors identified during this project. Characteristics of receptor activation by ligands will be studied and related to consumer sensory perception of these ligands. Ultimately the yeast system could be used as a biological model of human flavour perception, and in this way could provide a useful tool to the food industry in the development of new flavourings.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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