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Award details
Characterisation of flavour receptors
Reference
BBS/E/F/03018364
Principal Investigator / Supervisor
Professor Ian Connerton
Co-Investigators /
Co-Supervisors
Institution
Quadram Institute Bioscience
Department
Quadram Institute Bioscience Department
Funding type
Research
Value (£)
148,790
Status
Completed
Type
Institute Project
Start date
01/04/1998
End date
31/03/2002
Duration
48 months
Abstract
The human genome is thought to contain as many as 500 different genes for flavour receptors, yet only a few have been identified and characterised. This project involves the cloning and functional expression of genes involved in the primary reception of odorant and taste molecules. All know vertebrate olfactory receptors and many gustatory receptors share a common seven transmembrane structure. A model system to study such receptors in yeast is under development. This system will be used in parallel to mammalian cell systems to identify specific ligands for orphan flavour receptors identified through this project. Characteristics of receptor activation by ligands will be studied and related to consumer sensory perception of these ligands. Ultimately in vivo systems could be used as biological models of human flavour perception, and in this way could provide a useful tool to the food industry in the development of new flavourings.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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