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Molecular genetic analysis of bifidobacteria & their antimicrobials for enhanced colonic health
Reference
BBS/E/F/02200848
Principal Investigator / Supervisor
Professor Michael Gasson
Co-Investigators /
Co-Supervisors
Institution
Quadram Institute Bioscience
Department
Quadram Institute Bioscience Department
Funding type
Research
Value (£)
38,824
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
31/03/1999
Duration
24 months
Abstract
The lactic microflora of the human gut includes species that have a positive effect on human health. Of these species the bifidobacteria constitute a group of numerically and physiologically important microorganisms in the human large intestine. With increased interest in functional foods the positive role of these bacteria in human health is attracting considerable attention. Historically probiotic properties have been claimed for these bacteria with a range of benefits that include the inhibition of established and transient pathogens in the gastro-intestinal tract. This project will initiate a molecular genetic and physiological study of bifidobacteria drawing upon both established and new multidisciplinary skills in IFR. The research programme will focus on the development of basic molecular genetics in the bifidobacteria, genetic labelling so that the presence of particular strains can be monitored and investigation of broad spectrum antimicrobials that are produced by some strains of Bifidobacterium.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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