Award details

Manipulation of lipid metabolism aimed at production of fatty acids and polyketides for industrial use and for application in functional foods

Reference	BBS/E/F/02200650
Principal Investigator / Supervisor	Dr D Archer
Co-Investigators / Co-Supervisors	Dr A MacKenzie, Professor Michael Schweizer
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	154,768
Status	Completed
Type	Institute Project
Start date	01/04/1997
End date	31/10/1998
Duration	19 months

Abstract

The aim of this project is to investigate metabolic switching and pathway manipulation in yeasts, filamentous fungi and plants which focus on the production of fatty acids and polyketides concentrating on fatty acid synthase (FAS), polyketide synthase (PKS), diacylglycerol transferase (DAGAT) supply of acetyl-CoA and the ability to produce fatty acids of predetermined chain length and degree of desaturation. The programme will bring together laboratories in three countries with expertise in enzymology, biochemistry, physiology and molecular biology relating to the central thrust of the research. By combining the strength of each laboratory the aim will be to programme yeast, moulds and plants for production of particular (including novel) fatty acids and polyketides in required amounts. Realisation of this objective requires improved understanding of the relevant metabolism, pathway manipulation and flux control.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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