Award details

Diagnosis of spongiform enecephalopathy, scrapie & Creutzfeldt-Jacob syndrome in cows, sheep & humans respectively with therapeutic implications

Reference	BBS/E/F/02157195
Principal Investigator / Supervisor	Professor Mike Morgan
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	1,932
Status	Completed
Type	Institute Project
Start date	01/02/1998
End date	31/03/1998
Duration	2 months

Abstract

This is an EU Demonstration project which is designed firstly to evaluate two ELISAs to be used for detection of BSE in cattle and scrapie in sheep. One ELISA detects a prionin protein in blood which is believed to be crucial in the conversion of prion proteins (PrP) to (PrPsc), and the other detects antibodies to the prionin protein in the animal's blood. Further aims are to use the ELISAs to establish the distribution and extent of latent disease in EC herds, and to demonstrate that the same diagnostic system can detect the CJD related prionin in humans. The project is coordinated by Dr Johanna Bergmann and Dr Enrique Preddie at Hamburg University and there are two other partners. IFR is acting as a sub-contractor to provide an independent validation of the tests by assessing the ELISA data and matching it with different categories of animals, depending on their exposure to BSE or scrapie.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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