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The Dynamic Gastric Model: A physical and biochemical model of digestion in the stomach

Reference	BBS/E/F/00044481
Principal Investigator / Supervisor	Professor Peter Wilde
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	19,900
Status	Completed
Type	Institute Project
Start date	01/04/2010
End date	31/03/2013
Duration	36 months

Abstract

An advanced physical model of gastric digestion has been developed by IFR – the Dynamic Gastric Model (DGM). This is a sophisticated computer controlled in vitro model which accurately emulates the dynamic physical and biochemical conditions encountered during gastric digestion. It is utilised primarily in conjunction with static biochemical models of the duodenum to investigate in vitro bioaccessibility of bioactive compounds including nutrients, pharmaceuticals and pre- and probiotics. This project aims to expedite the refinement and validation of the model, in conjunction with Plant Biosciences Ltd (PBL). The project facilitates the acquisition and implementation of externally funded academic and commercial projects, it provides resource to ensure validity and consistency of the results wherever possible, and to provide knowledge and information for the further development and refinement of the DGM for future commercial opportunities.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Diet and Health
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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