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Award details
Exploitation of Lactobacillus johnsonii for competitive exclusion of pathogens and improvement of poultry health status
Reference
BBS/E/F/00042559
Principal Investigator / Supervisor
Professor Arjan Narbad
Co-Investigators /
Co-Supervisors
Institution
Quadram Institute Bioscience
Department
Quadram Institute Bioscience Department
Funding type
Research
Value (£)
49,300
Status
Completed
Type
Institute Project
Start date
15/06/2010
End date
31/01/2012
Duration
20 months
Abstract
The poultry GI tract represents a major reservoir of Campylobacter jejuni, the principle causative agent of food borne human disease and Clostridium perfringens which causes necrotic enteritis (NE) in poultry and food borne infection in humans. Withdrawal of antibiotic growth promoters has resulted in resurgence in incidence of NE which is detrimental to animal welfare. Our current work has highlighted the potential of a commensal Lactobacillus strain to competitively exclude C. perfringens and Campylobacter jejuni. We propose to expand the animal tests to assess the strain's potential in controlling these organisms and to address the problem of coccidiosis. We also aim to assess its role in promoting gut health through alteration of the poultry gut microbiota and its role in modulation of the host immune system.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
Animal Health, Microbial Food Safety, Microbiology
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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