Award details

The Model Gut

Reference	BBS/E/F/00042238
Principal Investigator / Supervisor	Dr Martin Wickham
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	695,891
Status	Completed
Type	Institute Project
Start date	01/04/2005
End date	31/03/2010
Duration	60 months

Abstract

The project will generate significant business opportunities and future revenue by aggressively identifying licensing opportunities for the technology, and in parallel, by providing a cost-effective service to customers who have a need for in-depth information on the rate, site and extent of digestion of their food or pharmaceutical product. The Model will provide an accurate and meaningful method for predicting the fate of compounds, nutrients and formulae prior to absorption. It is the first model developed to combine new and emerging scientific knowledge of the physical, mechanical, and biochemical environments experienced by the luminal contents, and therefore provides the first true simulation of the human gut. It is also the first model available that can handle real foods and pharmaceutical preparations and is also the only model that allows access at any stage of digestion, permitting sample collection and analysis at any time point. These unique design aspects fulfil a long required market need for a simulation that can be used to provide in-depth understanding of how physical, chemical and biochemical mechanisms interact during digestion, release and absorption of compounds from chemically and structurally complex food or drug preparations.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	Diet and Health, Pharmaceuticals, Technology and Methods Development
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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