Award details

Phytochemicals and Human Microbial Communities

Reference	BBS/E/F/00042219
Principal Investigator / Supervisor	Dr Paul O'Maille (JIC)
Co-Investigators / Co-Supervisors	Professor Richard Mithen
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	133,100
Status	Completed
Type	Institute Project
Start date	01/04/2009
End date	31/03/2010
Duration	12 months

Abstract

Terpeniods are the most structurally diverse class of plant natural products with a broad range of biological activities ranging from plant defences against pathogens, to pollinator attraction among myriad other roles in the chemical ecology. While these molecules often impart desirable flavour and fragrance properties to the foods we eat, little or nothing is known about their influence on healthy ageing in human populations. Of particular interest here are a subclass of terpenoids called the sesquiterpene phytoalexins (plant defence chemicals), some of which have demonstrated bacteriostatic potency against Helicobacter pylorri, the bacterium responsible for ulcers and gastric cancer. These investigations aim to define the chemical mechanisms of sesquiterpenes and explore the implications for human heath.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Diet and Health, Microbiology, Plant Science
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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