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ISPG/IIA Studentship: Chemo-protective effects of dietary isothiocyantes and selenium
Reference
BBS/E/F/00042195
Principal Investigator / Supervisor
Dr Ian Johnson
Co-Investigators /
Co-Supervisors
Dr Nigel Belshaw
Institution
Quadram Institute Bioscience
Department
Quadram Institute Bioscience Department
Funding type
Research
Value (£)
57,400
Status
Completed
Type
Institute Project
Start date
01/10/2007
End date
30/09/2010
Duration
36 months
Abstract
This study will investigate if a combination of selenium and isothiocyanates in cultured cells systems (human colon adenocarcinoma Caco-2 and hepatoma HepG2 cells) will offer additive or synergistic effects to improve antioxidant capacity. It will also allow us to determine the impact of these food components on epigenetic events such as DNA methylation and/or histone regulation, helping to identify changes in the regulation of gene expression.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
Diet and Health
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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