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ISPG/IIA Studentship: Bioimaging microbial-epithelial-immune cell interactions in the gastrointestinal mucosa

Reference	BBS/E/F/00042182
Principal Investigator / Supervisor	Dr Anastasia Sobolewski
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	78,300
Status	Completed
Type	Institute Project
Start date	01/10/2009
End date	30/09/2013
Duration	48 months

Abstract

How epithelial tissue regeneration occurs following injury or infection in the intestine is being investigated. Tissue explant models are being used to identify how stem cells, mucosal immune cells and microbes communicate to cause regeneration of the intestinal epithelium in response to pathogenic infection and inflammation. Bio-imaging of fluorescent transgenic tissue is being used to define the key spatial and temporal characteristics of microbial-epithelial-immune cell interactions involved in restoration of the epithelial barrier.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Diet and Health, Immunology, Microbiology, Stem Cells
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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