Award details

Lactic acid bacteria as GI tract delivery vehicles

Reference	BBS/E/F/00041772
Principal Investigator / Supervisor	Dr Jerry Wells
Co-Investigators / Co-Supervisors	Professor Michael Gasson
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	131,688
Status	Completed
Type	Institute Project
Start date	01/03/2004
End date	31/03/2005
Duration	13 months

Abstract

In recent years we have seen compelling evidence that components of the normal gut microflora and probiotic strains of lactic acid bacteria play an important role in the health of the host and exert potent effects on immune function in the gut. For example Lactobacilli, which are major components of the commensal microflora, are used as probiotics and have been shown to alleviate symptoms of allergic disease and reduce the development of type I allergy through their immunoregulatory properties. This research team has a particular interest in understanding the interplay between host immune function and the lactic acid bacteria. We will investigate in the mechanisms behind the health promoting properties of probiotics and explore their use as oral delivery vehicles for therapeutic proteins and vaccines

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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