Award details

Iron responsive gene regulation in Campylobacter

ReferenceBBS/E/F/00041657
Principal Investigator / Supervisor Professor Michael Gasson
Co-Investigators /
Co-Supervisors
Institution Quadram Institute Bioscience
DepartmentQuadram Institute Bioscience Department
Funding typeResearch
Value (£) 56,246
StatusCompleted
TypeInstitute Project
Start date 01/01/2004
End date 31/12/2006
Duration36 months

Abstract

Iron is an essential nutrient for all organisms and it plays a central role in metabolism, oxidative stress defence and global gene regulation. In Campylobacter, we need to understand the mechanisms of the iron-responsive Fur and PerR regulatory system and the role that iron plays in colonisation and virulence. The Fur-PerR system is an excellent model system to use to investigate regulatory networks in C. jejuni and one to which molecular genetic, bioinformatics and functional genomic tools can be applied. The aims of the project are to fully characterise iron-responsive gene regulation in Campylobacter and the promoter elements involved with a view to establishing knowledge led strategies for the control or eradication of Campylobacter.

Summary

unavailable
Committee Closed Committee - Agri-food (AF)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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