Award details

Bacterial functional genomics: Dissemination of cutting-edge technology (BACFUN)

Reference	BBS/E/F/00041407
Principal Investigator / Supervisor	Professor Jay Hinton
Co-Investigators / Co-Supervisors
Institution	Quadram Institute Bioscience
Department	Quadram Institute Bioscience Department
Funding type	Research
Value (£)	51,402
Status	Completed
Type	Institute Project
Start date	31/01/2002
End date	09/04/2006
Duration	50 months

Abstract

We have established an EU-funded Bacterial Functional Genomics Marie Curie Training Site at three adjoining centres, the Institute of Food Research (IFR), the John Innes Centre (JIC), and the Syngenta Genome Centre to disseminate this ground-breaking technology in the context of human health. The research environment includes classical microbiology, molecular biology and biochemistry integrated with the new genomics-based technologies such as DNA microarrays, proteomics and bioinformatics. Our 30 year experience of Salmonella, E. coli, Campylobacter and Streptomyces microbiology, biochemistry and genetics have recently been complemented by whole genome sequence information, leading to the establishment of Europe's best post-genomic facilities at the Norwich Research Park. Fellows will use genomic technologies such as DNA microarrays to ask: 1. Which genes do bacteria switch on to cause food poisoning or antibiotic production, or in response to environmental signals? 2. How does global bacterial gene expression respond to environmental factors? 3. Which bacterial virulence genes are induced by novel environmental factors relevant to disease? 4. What changes in gene expression accompany antibiotic production?.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search