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Award details
The induction and reactivation of primed non-cycling memory cells.
Reference
BBS/E/E/0CD/5/03
Principal Investigator / Supervisor
Professor Peter Beverley
Co-Investigators /
Co-Supervisors
Professor Arne Akbar
Institution
Edward Jenner Institute for Vaccine Res
Department
Scientific Head
Funding type
Research
Value (£)
12,000
Status
Completed
Type
Institute Project
Start date
01/01/2004
End date
31/12/2005
Duration
24 months
Abstract
Memory in humans persists for decades. Among CD8 T cells, a subset of so called CD45 revertant memory cells has been shown to be non-cycling, to have long telomeres and be resistant to apoptosis. In this project we shall study the role of cytokines and T cell co-stimulation in the generation of this population and will seek to identify a corresponding CD4 revertant memory population.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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