Award details

Mechanistic understanding of virus pathogenesis and resistance

ReferenceBBS/E/D/20241864
Principal Investigator / Supervisor Professor Paul Digard
Co-Investigators /
Co-Supervisors
Institution University of Edinburgh
DepartmentThe Roslin Institute
Funding typeResearch
Value (£) 1,214,789
StatusCompleted
TypeInstitute Project
Start date 01/04/2012
End date 31/03/2017
Duration59 months

Abstract

Endemic and exotic virus diseases pose a major threat to the livestock industry worldwide and in the case of potential zoonoses impinge on wider human welfare. Understanding mechanisms of virus pathogenesis in mammals and birds has major implications for identifying strategies that can translate to the clinic. We will i) exploit Roslin’s expertise in post genomic technologies to identify new viruses of veterinary importance, ii) map the viral genes associated with disruption of the innate immune response (PRRSV, influenza virus), iii) investigate the role of small non-coding RNA in beta- and gamma-herpesvirus infection and iv) explore the epidemiology and aetiology of newly discovered viruses.

Summary

unavailable
Committee Not funded via Committee
Research TopicsAnimal Health, Immunology, Microbiology
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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