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Regulatory networks in development - Animal Diseases, Developmental Biology, Genomic Proteomics and Metabolomics, Systems Biology, Stem Cells

Reference	BBS/E/D/05251445
Principal Investigator / Supervisor	Professor Christopher Whitelaw
Co-Investigators / Co-Supervisors
Institution	University of Edinburgh
Department	The Roslin Institute
Funding type	Research
Value (£)	1,955,631
Status	Completed
Type	Institute Project
Start date	01/08/2008
End date	31/03/2012
Duration	44 months

Abstract

We aim to integrate different developmental processes to enable prediction of function at the level of tissues and systems through exploiting genomic and bioinformatic expertise to develop an understanding of the signalling networks underlying cellular differentiation in animals. The integration of different developmental processes, between tissues and across different species, will enable better prediction of function at the level of tissues and systems. We aim to build understanding of cellular differentiation through comparative studies, exposing evolutionary regulatory networks. The objectives of the theme are: To define miRNA interactions in cell and tissue differentiation. To define transcriptional networks underlying macrophage differentiation. To generate centrosome network model. To investigate the regulation of gene expression in limb development.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	Stem Cells
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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