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Award details
Stem cell biology - Ageing, Developmental Biology, Genetically Modified Animals, Stem Cells, The 3Rs
Reference
BBS/E/D/05251442
Principal Investigator / Supervisor
Professor Christopher Whitelaw
Co-Investigators /
Co-Supervisors
Institution
University of Edinburgh
Department
The Roslin Institute
Funding type
Research
Value (£)
1,854,310
Status
Completed
Type
Institute Project
Start date
01/08/2008
End date
31/03/2012
Duration
44 months
Abstract
We aim to study the fundamental principles which control animal cell growth and diffrentiation. The experimental ability to investigate in vitro the molecular events determining and controlling cellular division and differentiation is extremely powerful in the study of biological function. In this regard, stem cells provide a unique experimental resource to tease apart the molecular mechanism controlling how a cell survives. In addition, intervention strategies based on stem cells have the potential to contribute new treatments of disease. The objectives of the theme are: To characterise signalling cross-talk in stem cell growth and differentiation. To derive ES/iPS cells from non-permissive species. To investigate germ cell development in vitro and in vivo.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
Stem Cells
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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