Award details

Designing oilseeds for nutrition and health

Reference	BBS/E/C/00005207
Principal Investigator / Supervisor	Professor Johnathan Napier
Co-Investigators / Co-Supervisors
Institution	Rothamsted Research
Department	Rothamsted Research Department
Funding type	Research
Value (£)	4,314,736
Status	Completed
Type	Institute Project
Start date	01/04/2012
End date	31/03/2017
Duration	59 months

Abstract

The primary objective of this project is to increase the nutritional composition of oilseeds by genetic modification. This will involve iterative metabolic engineering, underpinned by a dedicated lipidomics platform. Efficacy will be determined through collaborations with external partners, using animal feeding studies. The objectives of this research are: 1. The accumulation of 15% EPA and/or 10% DHA in transgenic Camelina sativa, validated by ACRE-approved field trials 2. To identify new enzyme activities which contribute to enhanced accumulation of non-native fatty acids in transgenic plants 3. To establish a dedicated and specific lipidomic platform for the systematic analysis of our transgenic plants, and use these datasets to populate metabolic models 4. To define the role of endogenous very long chain fatty acids in plant development 5. To identify genetic factors that significantly impact on the oil composition and content of oilseeds. 6. To incorporate information on lipid catabolism into systems analyses of lipid metabolism

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Crop Science, Plant Science, Synthetic Biology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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