Award details

Metabolomic technology development and the departmental analytical spectroscopy service

Reference	BBS/E/C/00004976
Principal Investigator / Supervisor	Professor Michael Beale
Co-Investigators / Co-Supervisors	Dr Jane Ward
Institution	Rothamsted Research
Department	Rothamsted Research Department
Funding type	Research
Value (£)	580,698
Status	Completed
Type	Institute Project
Start date	01/04/2008
End date	31/03/2012
Duration	48 months

Abstract

The analysis of metabolites is central to plant science research. The project concerns the development and application of the technology involved in high-throughput metabolite analysis. The work of the team has two elements:- 1. Research and development of metabolomics technology for plant and crop systems analysis. 2. Provision of an internal NMR and MS service for targeted metabolite analysis Research is focussed on the development of NMR, MS and associated data-handling methods for metabolomic fingerprinting of plant extracts. Novel techniques for increasing coverage and throughput of metabolomic data collection, and in downstream data processing, analysis and biological context interpretation are priorities. Using model plants (e.g. Arabidopsis) the project aims to establish methods and demonstrate application of metabolomics in gene function analysis, trait analysis, metabolic dynamics, plant development and responses to stress and disease. Methodologies are applied to crop science programmes and contribute to understanding, at the molecular level, of quality traits, including those concerning diet and health, effect of GM, nutrient uptake, disease and environmental interactions and biofuel improvement. The departmental analytical service (a function distinct from the metabolomics research) provides MS and NMR equipment maintenance and technical assistance to support research groups requiring targeted metabolite analysis.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	Crop Science, Plant Science, Technology and Methods Development
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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