Award details

Lipid-derived signalling

ReferenceBBS/E/C/00004949
Principal Investigator / Supervisor Professor Johnathan Napier
Co-Investigators /
Co-Supervisors
Institution Rothamsted Research
DepartmentRothamsted Research Department
Funding typeResearch
Value (£) 959,139
StatusCompleted
TypeInstitute Project
Start date 01/04/2008
End date 31/03/2012
Duration48 months

Abstract

Objectives: 1. Defining the role of genes induced by the volatile cis-jasmone (cJ). Transgenic arabidopsis plants will be generated in which cJ-induced genes are ectopically expressed. These lines will be subject to biochemical and metabolomic characterisation, and will also be used in plant-insect studies 2. Defining the signalling pathway utilised by cis-jasmone to effect changes in Arabidopsis gene expression. Candidate transcription factors (such as WRKY, ORCA, MYB and TGA classes) will be evalutated for their contribution to this signalling pathway via reverse genetics. Natural variation between Arabidopsis ecotypes will also be used to identify loci involved in responding to this signal. 3. Defining the role of sphingolipids and sphingolipid long chain bases in plants. Arabidopsis mutants defective in the synthesis of specific sphingolipids will be isolated and characterised at the biochemical and cellular level. Specifically, the role of sphingosine and S-1-P will be defined in plants.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsPlant Science
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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