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BBSRC CASE studentship: Investigation of fungal genes involved in wheat infection by Mycospaerella graminicola

ReferenceBBS/E/C/00004767
Principal Investigator / Supervisor Professor Kim Hammond-Kosack
Co-Investigators /
Co-Supervisors
Dr Jason Rudd
Institution Rothamsted Research
DepartmentRothamsted Research Department
Funding typeResearch
Value (£) 1,263
StatusCompleted
TypeInstitute Project
Start date 01/10/2005
End date 30/09/2008
Duration36 months

Abstract

Agrobacterium-mediated gene deletion will be established to test the roles of candidate fungal genes in pathogenicity and/or virulence against wheat. Gene deletion mutants will be further characterised at both the biochemical and molecular levels. This project will investigate the roles of a number of fungal genes involved in reactive oxygen species (ROS) generation, tolerance and damage repair including; superoxide dismutases, NADPH oxidases, peptide methionine sulfoxide reductase, and redox-sensitive trancription factors (homologues of yeast Yap1). Detailed expression analysis will also be performed to investigate the role of ROS in controlling fungal gene expression via both microarray and PCR approaches.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsCrop Science, Plant Science
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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