Award details

Characterisation of plant -virus- vector relationships, with particular respect to transmission by plasmodiophorids

Reference	BBS/E/C/00004206
Principal Investigator / Supervisor	Professor Kim Hammond-Kosack
Co-Investigators / Co-Supervisors	Dr Konstantin Kanyuka
Institution	Rothamsted Research
Department	Rothamsted Research Department
Funding type	Research
Value (£)	1,035,985
Status	Completed
Type	Institute Project
Start date	01/04/1999
End date	31/03/2007
Duration	96 months

Abstract

Plant viruses transmitted by root infecting plasmodiophorid vectors cause serious diseases, especially in cereal crops, in many parts of the world including the UK. Because the plasmodiophorids are obligate root-infecting parasites, the diseases are soil-borne and not amenable to chemical control. Resistance to the viruses is usually the only available control measure. Progress is hampered by lack of detailed knowledge about virus, plant and plasmodiophorid genes involved in the interaction. Objectives: 1) characterise the cereal viruses transmitted by plasmodiophorids, particularly the bymoviruses and furoviruses of barley and wheat. This will include studies to determine the molecular basis of resistance-breaking variants; 2) identify and characterise resistance to the viruses in cereal cultivars and related species. This will include identification of novel resistance sources for durable disease control, genetic mapping of resistance genes, development of molecular markers for resistance, and both molecular and biological characterisation of the resistance mechanism(s); 3) characterise the plasmodiophorid vectors of the viruses, principally various isolates of Polymyxa graminis. This will include studies of the ability of various isolates to transmit different viruses and the use of molecular biology to characterise and (where appropriate) discriminate between isolates; 4) characterise the association between the viruses and their plasmodiophorid vectors and determine the molecular and structural basis of transmission. The ultimate aim would be to develop a mechanistic model to explain how viruses are acquired from the host plant cell into the plasmodiophorid vector and then transmitted by delivery to a new host cell; 5) develop comprehensive databases for plant virus genome comparisons and to use these to identify genes and gene products related to common functions.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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