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Molecular genetics of interactions between plants and sedentary nematodes

Reference	BBS/E/C/00004183
Principal Investigator / Supervisor	Professor Brian Kerry
Co-Investigators / Co-Supervisors	Dr Rosane Curtis
Institution	Rothamsted Research
Department	Rothamsted Research Department
Funding type	Research
Value (£)	1,102,304
Status	Completed
Type	Institute Project
Start date	01/04/1999
End date	31/03/2008
Duration	108 months

Abstract

To overcome the lack of suitable molecular tools to understand plant-nematode interactions progress has been made through the production of monoclonal antibodies against nematode secretions and of a public collection of PCN Expressed Sequence Tags (ESTs). These will help to characterise the functions of nematode genes involved in parasitism. Research has focused on the identification of cyst nematode secretions and for the first time shown that the parasitic second stage-juveniles and adult females abundantly secrete proteins in planta. More importantly, these nematode secretions were localised around the root cells forming the nematode feeding site. Antibodies reactive to secretions from the nematode cuticle and amphids stopped nematode movement and penetration of plant roots. The genes encoding these proteins are being characterised and the potential of these antibodies evaluated as anti-nematode genes. Avirulence genes from plant nematodes can also have pathogenicity functions in the susceptible interaction. We are interested in the nature of these avirulence genes and their possible function(s) during the resistance and susceptible interactions.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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